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Reference information only. Therapept does not sell peptides and does not provide medical advice.Research-use notice

Therapept

Guides

Learn

How to read the documentation this sector produces — what each analytical method actually shows, what a certificate of analysis can and cannot support, and how to evaluate a supplier without relying on their own claims.

Testing & documentation

HPLC Purity vs Net Peptide Content

Chromatographic purity is a share of detector response. Net peptide content is a share of mass. They answer different questions and are often not both present.

12 Sept 2026 · 7 min

Testing & documentation

LC-MS Identity Verification on Peptide Certificates

Mass spectrometry supports identity when an observed value is reported against a calculated mass. “Conforms” without a number is a verdict with the work omitted.

12 Sept 2026 · 7 min

Testing & documentation

Lot-Level Documentation

A certificate is about a sample. Lot-level documentation is the join from that sample to a production run and to the container you can hold.

12 Sept 2026 · 6 min

Research literacy

Understanding Peptide Study Design

Study design is the first filter on a peptide paper. Species, n, endpoint and control structure decide what the paper can support — not the abstract’s adjectives.

12 Sept 2026 · 8 min

Research literacy

What “In Vitro” Means

In vitro means in glass: a cell, enzyme or biochemical system. Human cells in a dish are still an in-vitro study. They are not a clinical trial.

12 Sept 2026 · 5 min

Research literacy

Why Evidence Quality Differs Across Peptides

Approved peptide drugs have Phase 3 programmes and labels. Many research-chemical names have rodent literature and a withdrawn compounding nomination. That is a difference in the public record, not a ranking Therapept invented.

12 Sept 2026 · 6 min

Regulatory

503A, 503B and Compounding Categories

Pharmacy compounding in the United States is not FDA approval. Category 1, 2 and 3, 503A and 503B, and a PCAC vote are different instruments.

12 Sept 2026 · 8 min

Regulatory

How Regulatory Status Differs by Compound

The library contains FDA-approved drugs, discontinued approvals, active Category 2 substances, and unapproved names with withdrawn compounding nominations. Status is per compound.

12 Sept 2026 · 6 min

Supplier research

Peptide Supplier Documentation Standards

The standard is boring: lot-specific reports, a named laboratory, method, and a lookup that does not depend on the seller. Completeness is not a recommendation.

12 Sept 2026 · 7 min

Methodology

How Therapept Directories Are Built

Every factual claim carries a source. Unknown is a value. Provenance is rendered. Directories are not ranked.

12 Sept 2026 · 6 min

Testing & documentation

How to Read a Peptide Certificate of Analysis

A certificate of analysis is a record of specific tests run on a specific lot. Here is what each field means, which fields are load-bearing, and the four ways a COA can be technically accurate and still tell you very little.

3 Sept 2026 · 9 min

Testing & documentation

HPLC vs LC-MS: What Each Test Actually Tells You

HPLC and LC-MS are not competing methods or tiers of the same measurement. They answer different questions — how much of one thing, and which thing — and a purity figure without an identity confirmation is a known blind spot.

3 Sept 2026 · 8 min

Supplier research

How to Evaluate a Research Peptide Supplier

Most supplier comparisons rank marketing. This is a checklist of things a supplier either can or cannot produce on request — and the distinction between evidence, self-reported claims, and design choices that look like evidence.

3 Sept 2026 · 10 min

Regulatory

What “Research Use Only” Actually Means

The phrase is treated as a legal shield across the sector. Its actual regulatory footing is much narrower than that, and what a product is marketed for matters more to regulators than what the label says.

3 Sept 2026 · 7 min

Testing & documentation

How Peptide Batch and Lot Traceability Works

A lot number is only useful if it resolves to something. This covers what a lot actually is, what a working traceability chain looks like end to end, and the difference between a lookup tool and lookup theatre.

3 Sept 2026 · 7 min

Testing & documentation

A Guide to Third-Party Peptide Testing

Independent testing is the only way to check a supplier's documentation rather than trust it. What to order, how to choose a laboratory, what it costs you in sample and time, and the limits of a single result.

3 Sept 2026 · 8 min