Copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine
GHK-Cu
A copper complex of the tripeptide GHK. Authoritative records represent the complex in several non-equivalent ways, so molecular formula and mass depend on which representation a document is using.
Also listed as: Copper tripeptide-1, Prezatide copper, Copper peptide
Chemical identity
- Compound class
- Copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine. Cosmetic ingredient under the INCI name Copper Tripeptide-1
- Sequence
- Gly-His-Lys, complexed to Cu(II)
- Molecular formula
- C14H23CuN6O4+ (prezatide copper, PubChem CID 71587328)
- Molecular weight
- 402.92 g/mol (as prezatide copper)
- CAS number
- 89030-95-5 (copper complex) · 49557-75-7 (uncomplexed GHK)
- PubChem CID
- 71587328
- Research categories
- Metal-peptide complexes, Cosmetic ingredients
United States regulatory status
No FDA-approved product
- No approved drug product exists in Drugs@FDA.
- Listed on FDA's table of bulk substances nominated for compounding and withdrawn by the nominator. FDA's entry is scoped specifically to injectable routes of administration.
- FDA's published concerns include immunogenicity risk from aggregation and impurities, and limited human data.
- Not named on the WADA 2026 Prohibited List.
Regulatory status describes how a substance is classified. It is not a safety assessment, and it says nothing about the quality of any particular material.
Sources
Last reviewed 3 September 2026 · Compiled by Therapept Editorial · How these records are built