Selank + Semax

Why people combine them

Two Russian-developed heptapeptides discussed together for cognition, anxiety and focus. Semax is a registered product in some jurisdictions; Selank is not. Both appear on FDA's withdrawn-nominations compounding table.

Evidence for the combination

This pairing rests entirely on community practice. No published study and no registered trial of the combination is indexed by Therapept.

Evidence for each component

• Selank — Tuftsin analogue; preclinical and small human literature largely from the originating research groups; no approved product in the United States.
• Semax — ACTH(4-10) analogue; used as a registered product in some other jurisdictions; no United States approval.

Commonly reported dosing and protocols

Displayed source by source. Therapept does not compose these into a recommended protocol.

• COMMUNITYReddit / nootropic forums (recurring)

  Posts commonly describe intranasal use of both, sometimes in the same solution, at amounts quoted in drops or micrograms that vary widely.

  Reported practice. Intranasal use of research materials carries its own sterility and formulation questions that the community threads do not answer.

  Checked 17 September 2026 · Community sources — see the dosing reference for limitations

Potential overlap and concerns

• Both substances are on FDA's withdrawn-nominations table with published immunogenicity and safety-information concerns.
• Neither has a United States approved product; sterile intranasal self-formulation is unregulated practice.