- Population
- 3 normal male volunteers
- Route
- Subcutaneous
- Dose as published
- Starting 0.01 mg/kg; two subjects escalated in 0.005 mg/kg steps to 0.03 mg/kg, one to 0.025 mg/kg
- Frequency
- Alternating-day schedule, Monday–Friday, for 2 consecutive weeks
- Endpoint
- Tanning response; adverse events (somnolence, nausea, spontaneous erections)
Melanotan II · dosing reference
What dose information exists for Melanotan II?
A pilot Phase I study exists; no approved product. The study's own conclusion was about dose selection for future Phase I work, not therapy.
Published human study doses
Human studyIntervention parameters reported in individual published human studies. Each study stays separate; parameters are never aggregated across studies.
Community-reported ranges
CommunityWhat people report discussing or doing in forums, on Reddit and in videos. Included only to show demand and reported practice — never as clinical evidence.
Widely discussed around roughly 0.25–1 mg per day during initial loading periods, then less frequently
- FDA's published entry for melanotan II references case reports of serious adverse events; community discussion generally does not engage with them.
Community reports describe what people say they are doing. They are not equivalent to clinical evidence, and discussion volume says nothing about whether a practice is safe, effective or even real.
Why community reports are shown at all
People search for dose information before they search for anything else in this sector. Where discussion is widespread, pretending it does not exist helps nobody. Therapept reports the discussion — its rough shape, how common it is, and where it happens — while keeping it visibly separate from every other kind of source. Community reports describe what people say they are doing. They are not equivalent to clinical evidence.
Last reviewed 17 September 2026 · Compiled by Therapept Editorial · How these records are built
