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Melanotan II · dosing reference

What dose information exists for Melanotan II?

A pilot Phase I study exists; no approved product. The study's own conclusion was about dose selection for future Phase I work, not therapy.

Published human study doses

Human study

Intervention parameters reported in individual published human studies. Each study stays separate; parameters are never aggregated across studies.

Human studyDorr et al., Life Sciences (1996)
Population
3 normal male volunteers
Route
Subcutaneous
Dose as published
Starting 0.01 mg/kg; two subjects escalated in 0.005 mg/kg steps to 0.03 mg/kg, one to 0.025 mg/kg
Frequency
Alternating-day schedule, Monday–Friday, for 2 consecutive weeks
Endpoint
Tanning response; adverse events (somnolence, nausea, spontaneous erections)

Community-reported ranges

Community

What people report discussing or doing in forums, on Reddit and in videos. Included only to show demand and reported practice — never as clinical evidence.

Community reportedmoderate discussion volume

Widely discussed around roughly 0.25–1 mg per day during initial loading periods, then less frequently

  • FDA's published entry for melanotan II references case reports of serious adverse events; community discussion generally does not engage with them.
Reddit · Tanning forums · YouTube · Last checked 17 September 2026

Community reports describe what people say they are doing. They are not equivalent to clinical evidence, and discussion volume says nothing about whether a practice is safe, effective or even real.

Why community reports are shown at all

People search for dose information before they search for anything else in this sector. Where discussion is widespread, pretending it does not exist helps nobody. Therapept reports the discussion — its rough shape, how common it is, and where it happens — while keeping it visibly separate from every other kind of source. Community reports describe what people say they are doing. They are not equivalent to clinical evidence.

Last reviewed 17 September 2026 · Compiled by Therapept Editorial · How these records are built