- Population
- 8 healthy male volunteers at each of five infusion-rate levels
- Route
- Intravenous infusion
- Dose as published
- Intravenous infusions over 15 minutes at 4.21, 14.02, 42.13, 84.27 and 140.45 nmol/kg
- Frequency
- Single infusion per session (dose-escalation design)
- Endpoint
- Growth-hormone release pharmacodynamics (SC50 214 nmol/L; peak GH at 0.67 h)
Ipamorelin · dosing reference
What dose information exists for Ipamorelin?
No approved product exists. Human data are limited to pharmacology studies of the compound itself; everything beyond those studies comes from lower source tiers.
Published human study doses
Human studyIntervention parameters reported in individual published human studies. Each study stays separate; parameters are never aggregated across studies.
Published animal studies
AnimalClearly labelled animal research. Animal dosing is never visually mixed with human study data and is not evidence of human response.
- Species
- Rat (anaesthetised); pig (conscious)
- Route
- As described in the study's models
- Dose as published
- Rat ED50 80 ± 42 nmol/kg; pig ED50 2.3 ± 0.03 nmol/kg (GH-release dose-response)
Animal-study parameters describe what was given to animals under laboratory conditions. They are not evidence of how humans respond, and Therapept does not convert them into human equivalents.
Community-reported ranges
CommunityWhat people report discussing or doing in forums, on Reddit and in videos. Included only to show demand and reported practice — never as clinical evidence.
Discussed across a very wide span — roughly 100–300 mcg per day in most posts, sometimes paired with a GHRH analogue
- Reported ranges vary by orders of magnitude between communities and rarely cite a primary source.
- Therapept has not verified any of these reports and does not present them as evidence.
Community reports describe what people say they are doing. They are not equivalent to clinical evidence, and discussion volume says nothing about whether a practice is safe, effective or even real.
Why community reports are shown at all
People search for dose information before they search for anything else in this sector. Where discussion is widespread, pretending it does not exist helps nobody. Therapept reports the discussion — its rough shape, how common it is, and where it happens — while keeping it visibly separate from every other kind of source. Community reports describe what people say they are doing. They are not equivalent to clinical evidence.
Last reviewed 17 September 2026 · Compiled by Therapept Editorial · How these records are built
